Research and development

Reference

  • The moment that moved industrial researchers (Kagakudoujin) “Unique process for the development of optically active non-standard amino acids” Hisatosh Uehara, Yasumasa Dekishima, p. 201, 2017.
  • Org. Process Res. Dev. 2016, 20, 867−877 Masahiko Seki, [A New Catalytic System for Ru-Catalyzed C–H Arylation Reactions and Its Application in the Practical Syntheses of Pharmaceutical Agents]
  • ACS Catal. 2011, 1, 607–610, Masahiko Seki, [Highly Efficient Catalytic System for C–H Activation: A Practical Approach to Angiotensin II Receptor Blockers]
  • ACS Catal. 2014, 4, 4047−4050, Masahiko Seki, [Efficient Catalytic System for Ru-Catalyzed C–H Arylation and Application to a Practical Synthesis of a Pharmaceutical]
  • J Org Chem. 2011 Dec 16;76(24):10198-206,Masahiko Seki, Masaki Nagahama, [Synthesis of Angiotensin II Receptor Blockers by Means of a Catalytic System for C–H Activation]
  • Synthesis 2014, 46, 3249–3255, Masahiko Seki, [Novel and Efficient Debenzylation of N-Benzyltetrazole Derivatives with the Rosenmund Catalyst]
  • Synthesis 2015, 47, 2985–2990, Masahiko Seki, [2,4-Dimethoxybenzyl Group for the Protection of Tetrazole: An Efficient Synthesis of Olmesartan Medoxomil through C–H Arylation]
  • Synthesis 2015, 47, 1423–1435, Masahiko Seki, [Studies on the Cocatalyst in Ruthenium-Catalyzed C–H Arylation]
  • ACS Symposium Book Series, 2009, Chapter 22, 357-374, Mari Hara Yasuda ,Makoto Ueda, Kazuya Okano, Hisaaki Mihara, Nobuyoshi Esaki, [Enzymatic Synthesis of Unnatural Amino Acids]
  • Biotechnol Lett 2013, 35, 685–688, Toyokazu Yoshida, Koichi Mitsukura, Takuya Mizutani, Ryo Nakashima, Yasuyo Shimizu, Hiroshi Kawabata, Toru Nagasawa [Enantioselective synthesis of (S)-2-cyano-2-methylpentanoic acid by nitrilase]
  • Appl Microbiol Biotechnol. 2015 Jun;99(12):5045-54, Yasushi Tani, Ryoma Miyake, Ryoichi Yukami, Yasumasa Dekishima, Hideyasu China, Shigeki Saito, Hiroshi Kawabata, Hisaaki Mihara, [Functional expression of L-lysine αunctiona from Scomber japonicus in Escherichia coli for one-pot synthesis of L-pipecolic acid from DL-lysine. ]
  • Appl Environ Microbiol. 2016 Jan 22;82(7):2070-2077, Makoto Hibi, Ryosuke Mori, Ryoma Miyake, Hiroshi Kawabata, Shoko Kozono, Satomi Takahashi, Jun Ogawa, [Novel Enzyme Family Found in Filamentous Fungi Catalyzing trans-4-Hydroxylation of L-Pipecolic Acid ]
  • J Biosci Bioeng. 2019 Feb;127(2):145-149, Kohsuke Honda, Tomohiro Ono, Kenji Okano, Ryoma Miyake, Yasumasa Dekishima, Hiroshi Kawabata, [Expression of engineered carbonyl reductase from Ogataea minuta in Rhodococcus opacus and its application to whole-cell bioconversion in anhydrous solvents]
  • J Biosci Bioeng. 2017 Jun;123(6):673-678, Kohsuke Honda, Mizuha Inoue, Tomohiro Ono, Kenji Okano, Yasumasa Dekishima, Hiroshi Kawabata, [Improvement of operational stability of Ogataea minuta carbonyl reductase for chiral alcohol production]

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