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CDMO business
Manufacturing equipment
We offer the Safe, Stable, Low-cost, and High-quality APIs and intermediates at our cGMP-compliant multipurpose plants. We supply APIs and intermediates under Quality assurance to all steps such as raw material procurement, manufacturing, processing, and shipping.
Commercial plant
Reaction / technology
Dangerous reactions
Tetrazolization,diazotization,nitration,hydrogen reduction,Grignard,reaction
Others
Amination,alkylation,imidization,iminoethylation,ethylation,esterification,carbamoylation,sulfonation,dehalogenation,thioamination,disulfidization,nitrosylation,Friedel–Crafts reaction,Sandmeyer reaction,hydroboration,halogenation,hydrazine,condensation,methylolation,salt synthesis,hydrolysis,reduction synthesis,optical separation,acid amination,acid chloride,decarboxylation,Kolbe–Schmitt,reaction, etc.
Substances (examples)
Water-reactive reagents: n-BuLi, sec-BuLi, 60% NaH, etc.
Fire Services Act Class 5 Dangerous Goods: Organic peroxides, NaN3,
hydroxylamine hydrochloride, etc.
Other: Phosphorus pentasulfide, inorganic CN compounds, diborane, bromine, etc.
Equipment
Reactor
0.5–20 m3
GL, Stainless steel, HC equivalent Anchor blade, Three-blade retreat impeller, Highly-efficient multifunctional mixing impeller, etc.
Filter (Centrifuge)
24–48 inches
Stainless steel, HC equivalent, Teflon lining vertical centrifuge (upper exhaust and lower exhaust types)
Drying equipment
1–7 m3
Stainless steel, HC equivalent, Teflon lining vertical centrifuge (upper exhaust and lower exhaust types)
Mills
16
Pin mill, cutter mill, hammer mill, jet mill, etc.
Clean room
9
Maintained at Class 100,000
Temperature Range
–80 to 180℃
UTT: liquid nitrogen, brine, chilling water, steam (190℃)
Operating pressure
FV approx. 0.99 Mpa
Pilot plant
Reaction / technology
Same as that of commercial facilities and as per clients’ requests
Substances
As per clients requests
Equipment
Reactor
100–8000 L
GL: Total 50 m3
Stainless steel: Total 30 m3Anchor blade, Three-blade retreat impeller, Highly-efficient multifunctional mixing impeller, Molepaw blade, etc.
Filter (Centrifuge)
24–42 inches
Stainless steel, HC equivalent
Drying equipment
200–850 L
GL
Mills
4
Pin mill, cutter mill, hammer mill, jet mill
Clean room
1
Maintained at Class 100,000
Temperature Range
–80 to 180℃
UTT: Liquid nitrogen, brine, chilling water, steam (190℃)
Operating pressure
FV approx. 0.97 MPa
Analytical Equipment
Chromatography system
High Performance Liquid Chromatography (HPLC）, Ultra High Performance Liquid Chromatography (UHPLC), Gas Chromatography (GC), Ion Chromatography (IC)
Spectral photometer
Fourier Transform Infrared Spectroscopy (FT-IR), UV-vis Spectrophotometer, Polarimeter, Refractometer, Color difference meter
Powder Analysis
X-Ray Powder Diffraction, Particle counter
Nuclear Magnetic Resonance
400MHz-NMR
Mass Spectrometer
Inductively Coupled Plasma Mass Spectrometry (ICP/MS), Liquid Chromatography-Mass spectrometry (LC-MS), Gas Chromatography - Mass spectrometry (GC/MS)
Thermal Analysis
Differential Scanning Calorimetry (DSC), Thermogravimetry/Differential Thermal Analysis (TG/DTA)
Others
pH meter, Melting point apparatus, TOC analyzer, Karl Fischer titrator (volumetric and coulometric), Titrator, Hydrometer, Electrical conductivity meter
